The angel in this painting calls out people’s callings and destiny with the music flowing from her instrument. There is fire coming from the guitar that the angel is holding. This is a promise to you that God's calling will always be accompanied with a fire of passion that will light up your soul and awaken your heart. It is time to respond from the music that you hear from God. 
So listen to your heart and follow it.

Psalm 57:8
“Wake up, my heart! Wake up, O lyre and harp! I will wake the dawn 
with my song.”